First Appearance:
Werewolf by Night #13

First Dr. Strange appearance:
Doctor Strange (vol. 1) #75

Latest Appearance:
Dr. Strange vol. 2, Flight of Bones, #1-4

Profile:
Topaz is a powerful empath with healing abilities, who was raised from childhood by the sorcerer Taboo.  She has had encounters with Werewolf by Night (Jack Russell), Dracula, Mephisto, and Dormammu.

Topaz was dragged into Hades to stop the threat of Dracula (TOD #62-64), and was trapped within a demon's body.   She was was able to escape with the help of Dr. Strange, but was separated from the empathic half of her soul  Finally, Strange restored her soul in an epic battle with the evil sorcerer Urthona (Dr. Strange vol. 1 #81).  However, in order to defeat Urthona and save his friends, Strange had to destroy most of his mystical objects of power.